. Author manuscript; available in PMC: 2022 Jul 30.

Published in final edited form as: Pharmacotherapy. 2021 Nov 17;42(1):14–22. doi: 10.1002/phar.2641

TABLE 2.

Patient characteristics

	Protocol
Characteristic	Alem-TBI (n = 12)	Pento-Cy-Alem-TBI (n = 10)
Male (%)	83	30
Age at HSCT (years), mean	32 (range 16–50)	34 (range 26–41)
Body mass index (kg/m²), mean	22.7 (range 16.1–39.2)	24.1 (range 19.5–29.1)
Genotype (%)
HbSS	75	100
HbSC	8	0
HbSβ°	17	0
Composition of infused graft
CD34+ cells (×10⁷)/kg body weight, mean	1.39 (range 0.60–2.58)	1.51 (range 0.91–2.92)
CD3+ cells (×10⁸)/kg body weight, mean	4.46 (range 2.22–13.3)	3.00 (range 1.53–5.46)

Abbreviations: Alem, alemtuzumab; Cy, cyclophosphamide; HSCT, hematopoietic stem cell transplant; Pento, pentostatin; TBI, total body irradiation.