figs1.

The regulatory network of miRNAs associated with severe COVID-19: correlation analysis

The comparative analysis of GSEA between cells derived from mild and severe COVID-19 shows that gene expression enriched in the group of mild patients (FDR <0.05) are the targets of 29 miRNAs. This Figure shows the fraction of target genes in common among the associated target genes of each of the 29 miRNAs. The miRNAs associated with each target gene set show high redundancy (green clusters). Therefore, there are only 11 target gene sets with low redundancy among themselves. We selected the corresponding 11 miRNAs listed to the right for the subsequent analyses