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. 2022 Jul 23;2022:6871269. doi: 10.1155/2022/6871269

Figure 4.

Figure 4

Inhibition of ROCK1 signal can downregulate M1-type polarization level of RAW264.7 macrophages. The proportion of CD11b+CD86+ cell subset of RAW264.7 macrophages was analyzed by flow cytometry after 5%, 10%, and 15% Elong mechanical stretch for 8 h. Control indicates cells were cultured at static condition. The (+) Y-27632 group was pretreated with Y-27632 (10 μM, 12 h). Quantitative analysis of the ratio of M1-RAW264.7 macrophages via the IDEA software. The results are expressed as the means ± SD (n = 3). Compare to control, ##P < 0.01. Compare to MS group, ∗∗P < 0.01.