Table 2.
Gastric, Small Bowel, and Colonic Transit in 166 Patients with MS (n refers to number with available data)
| Parameters | Normal values | Total group | Phase of MS | |||||
|---|---|---|---|---|---|---|---|---|
| Relapsing-remitting | Progressive | P# value | ||||||
| n | Median, IQR | n | Median, IQR | n | Median, IQR | |||
| GE 1h, % | 4.4–35.0 | 110 | 26.5 (18.0, 37.0) | 75 | 25.0 (18.0, 35.0) | 35 | 30.0 (18.0, 42.0) | 0.38 |
| GE 2h, % | 25.0–78.5 | 165 | 54.0 (34.5, 67.5) | 110 | 53.0 (34.0, 63.5) | 67 | 59.5 (43.7, 76.2) | 0.73 |
| GE 4h, % | 76.2–100 | 163 | 92.0 (81.0, 97.0) | 110 | 92.0 (80.0.3, 97.0) | 55 | 92.0 (82.0, 97.0) | 0.84 |
| CF 6h, % | 0–100 | 116 | 66.5 (38.0, 81.8) | 72 | 65.0 (38.0, 80.8) | 44 | 67.0 (33.5, 83.5) | 0.41 |
| GC 24h | 1.47–3.86 | 81 | 1.9 (1.4, 2.7) | 51 | 2.0 (1.4, 2.8) | 30 | 1.8 (1.5, 2.4) | 0.84 |
| GC 48h | 2.1–5.0 | 8 | 2.7 (2.0, 3.7) | 5 | 3.1 (2.0, 3.7) | 3 | 2.3 (1.6, 3.9) | 0.65 |
#
Group comparison of progressive and relapsing-remitting MS using two-sample t-test for GE and CF, and Wilcoxon rank sum test for GC.
GE=gastric emptying; GC=geometric center; CF=colonic filling at 6 hours is a surrogate for small bowel transit; normal values are from references 12 and 15.