Table 4.
Anorectal Manometry Measurements in Patients with MS (n refers to number with available data)
| Data median (IQR) | Mean anal sphincter pressure (resting), mmHg | Mean anal sphincter pressure (squeeze), mmHg | Rectoanal pressure differential, mmHg | Rectal balloon expulsion test, sec | ||||
|---|---|---|---|---|---|---|---|---|
| Normal Values 10th and 90th %ile^ | 33, 93 | 122, 281 | −64, 12 | <60 sec | ||||
| Patients with MS | n | Median (IQR) | N | Median (IQR) | n | Median (IQR) | n | Median (IQR) |
| Constipation | 33 | 65.2 (49.1, 82.2) | 10 | 85.6 (75.3, 95.4) | 22 | −32.0 (−43.8, −14.2) | 28 | 60 (22, 180) |
| Patients with slow colonic transit at 24h & | 3 | 65.2 (57.5, 114.4) | 1 | 69.3 | 2 | −32.4 (−58.4, −6.4) | 2 | 42.5 (25,60) |
| Patients with delayed gastric emptying at 4h & | 9 | 57.5 (24.4, 86.05) | 2 | 68.15 (67, 69.3) | 7 | −32.9 (−47.8, −2.4) | 8 | 42.5 (22, 60) |
| Constipation & fecal incontinence | 15 | 49.3 (29.4, 70.4) | 6 | 82.0 (64.7, 129.6) | 10 | −32.0 (−47.8, 0.8) | 15 | 180 (60, 180) |
| P value # | 0.07 | 0.7 | 0.46 | 0.78 | ||||
#
Group comparison using Wilcoxon rank sum test
^
Normal values for women >50 years old used to correspond to typical demographic of patients with MS who underwent anorectal manometry (data from reference 37).
&
Anorectal manometry data were available for only 3 patients with slow colonic transit and 9 patients with delayed gastric emptying.