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CR promotes proximal BM adiposity and an increase in serum adiponectin levels. (a) Representative images of osmium tetroxide stained tibias, (b) Total BMAT, (c) Proximal BMAT, (d) Distal BMAT, (e) Fasting serum adiponectin levels, (f) Fasting serum leptin levels, (g) Fasting serum IGF-1 levels. Error bars SEM, (a–d) n = 5/group, (e–g) n = 10/group, ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, Ordinary one-way ANOVA with Tukey’s multiple comparisons test.
