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. 2022 Jul 30;13:4435. doi: 10.1038/s41467-022-32176-5

Fig. 4. RBM3 suppresses lung ILC2s independent of adaptive immunity.

Fig. 4

Rag2−/− and Rbm3−/−Rag2−/− mice were challenged with 20 µg Alternaria four times over 10 days. Data representative of 4 mice per group. ac Total number of ILCs (p = 0.0029), Ki67 expressing ILCs (p = 0.0060), and type 2 cytokine-producing ILC2s (IL-5 p = 0.0008 and IL-13 p = 0.0145). Unpaired t-Test, two-tailed. d Total BAL (p = 0.0633) and lung (p = 0.0034) eosinophils. Unpaired t-Test, two-tailed. *p < 0.05, **p < 0.01, ***p < 0.001. Data are presented as mean values+/ SEM.