Table 8.
Cutaneous irritancy test.
| Rat | Negative control | Positive control | T1 | T2 | T3 | T4 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Er | Ed | Er | Ed | Er | Ed | Er | Ed | Er | Ed | Er | Ed | |
| 1 | 1 | 0 | 4 | 3 | 1 | 0 | 1 | 0 | 2 | 0 | 1 | 0 |
| 2 | 0 | 0 | 3 | 4 | 1 | 0 | 1 | 0 | 1 | 1 | 2 | 1 |
| 3 | 0 | 0 | 4 | 4 | 1 | 0 | 0 | 0 | 2 | 1 | 2 | 1 |
| 4 | 1 | 0 | 4 | 3 | 2 | 1 | 0 | 1 | 2 | 0 | 2 | 1 |
| 5 | 1 | 0 | 4 | 4 | 2 | 1 | 1 | 0 | 1 | 1 | 2 | 1 |
| 6 | 1 | 0 | 4 | 4 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
| Average | 0.66 | 0 | 3.83 | 3.66 | 1.33 | 0.5 | 0.66 | 0.166 | 1.5 | 0.66 | 1.66 | 0.66 |
| PII | 0.66 | ± 0.15 | 7.5+++ | ± 0.16 | 1.83†a | ± 0.12 | 0.83†a | ± 0.13 | 2.16†a | ± 0.14 | 2.33†a | ± 0.16 |
+++Significant (p < 0.001) when compared to group 1.
aSignificant (p < 0.001) when compared to group 2.
†Non-significant (p > 0.05) when compared to group 1.