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. 2022 Jul;47(4):328–337. doi: 10.30476/IJMS.2021.89898.2065

Table 2.

Prevalence and adjusted odds ratio (AOR) for the association between the status of opium consumption and coronary artery disease risk factors (KERCARD-Second Phase- 2014-2018, N=9996), Kerman, Iran

Risk factor Addiction status Risk factor prevalence Adjusted analysis
N (%) 95% CI AOR P 95% CI
Diabetes (normal versus diabetic) Nonuser 1384 (15.9) (15.1-16.7) 1
Occasional user 107 (21.8) (18.2-25.7) 1.1 0.2 (0.8-1.6)
Dependent user 146 (20.5) (17.5-23.6) 1.0 0.9 (0.7-1.4)
Depression (BDI<15 versus BDI>15) Non-user 1359 (15.6) (14.8-16.3) 1
Occasional user 74 (15.1) (12.0-18.5) 1.4 0.02 (1.0-2.0)
Dependent user 156 (21.9) (21.5-28.0) 1.9 0.001 (1.3-2.6)
Anxiety (BAI<7 versus BAI>7) Non-user 3600 (41.3) (40.2-42.3) 1
Occasional user 183 (37.3) (32.9-41.7) 1.0 0.5 (0.8-1.4)
Dependent user 287 (40.3) (36.6-43.9) 1.3 0.05 (0.9-1.7)
Hyper TG (TG<200 versus TG>200) Non-user 3314 (38.0) (36.9-39.0) 1
Occasional user 233 (47.5) (42.9-51.9) 1.1 0.3 (0.8-1.4)
Dependent user 311 (43.6) (39.8-47.2) 1.0 0.5 (0.8-1.3)
Poor HDL/LDL ratio (under 0.3 versus above 0.3) Non-user 7523 (87.1) (86.4-87.8) 1
Occasional user 413 (84.3) (80.7-87.3) 1.1 0.5 (0.8-1.5)
Dependent user 594 (83.9) (80.9-86.5) 0.9 0.8 (0.6-1.3)
Hypertension (BP<140/90 versus BP>140/90) Non-user 2514 (28.8) (27.8-29.7) 1
Occasional user 187 (37.5) (33.1-41.9) 0.9 0.4 (0.7-1.1)
Dependent user 291 (40.8) (37.1-44.4) 1.1 0.3 (0.8-1.5)
Poor GI (GI<1 versus GI>1) Non-user 2095 (29.4) (28.3-30.4) 1
Occasional user 144 (41.0) (35.8-46.3) 1.1 0.1 (0.9-1.5)
Dependent user 159 (51.0) (45.2-56.6) 1.6 0.001 (1.2-2.1)
High CPI (CPI<2 versus CPI>3) Non-user 468 (6.6) (5.9-7.1) 1
Occasional user 51 (14.4) (10.9-18.5) 1.1 0.6 (0.7-1.5)
Dependent user 68 (21.4) (17.0-26.3) 1.4 0.03 (1.0-2.0)
Overweight/obesity (BMI<25 versus BMI>25) Non-user 5755 (66.1) (65.1-67.1) 1
Occasional user 322 (65.8) (61.4-70.0) 0.9 0.8 (0.7-1.2)
Dependent user 378 (53.3) (49.5-57.0) 0.6 0.0 (0.4-0.8)
Low physical activity (Weekly min<150 versus>150) Non-user 4125 (47.3) (46.2-48.3) 1
Occasional user 233 (47.5) (42.9-51.9) 1.1 0.3 (0.9-1.4)
Dependent user 387 (54.2) (50.4-59.9) 1.4 0.001 (1.0-1.7)

The association between opium consumption and CAD risk factors was assessed using the Poisson regression model and adjusted odds ratios (according to potential confounders, such as age, sex, and other CAD risk factors, including serum lipids, level of physical activity, and level of psychological disorders). GI: Gingival inflammation index; CPI: Community periodontal index.