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. 2022 Jan 1;16(1):55–65. doi: 10.18502/ijhoscr.v16i1.8443

Table 3.

Prognostic Factors of overall survival (OS) in patients with AML after

Variable
Survival time
Univariate
Multivariate
Mean ± SD
(Months)
HR
(95% CI)
P-value HR
(95% CI)
P-value
Sex Male 58.06 ± 6.38 0.76 (0.41-1.40) 0.38
Female 42.97 ± 4.91 1
Age group of patients ≤ 30 52.69 ± 6.76 1.11 (0.61-2.04) 0.73
> 30 53.98 ± 5.94 1
Diseases status at
transplant
CR1 54.34 ± 4.56 0.69 (0.17-2.87) 0.61
CR2 20.52 ± 8.71 1
WBC (×108 /ml) <5 68.94 ± 5.82 1 1
5-10 26.00 ± 6.8 2.97 (1.23-7.19) 0.02* 2.76 (1.13-6.72) 0.03*
>10 22.09 ± 6.77 4.06 (1.88-8.80) <0.001* 3.98 (1.84-8.63) <0.001*
Donor relative Sibling 55.91 ± 4.67 0.48(0.20-1.14) 0.09
Related alternative 14.63 ± 4.61 1
Relapse Yes 25.11 ± 9.45 2.61 (1.28-5.34) 0.008* 5.66 (2.6-12.34) <0.001*
No 57.94 ± 4.79 1 1
Age group of donors ≤ 30 58.13 ± 6.86 0.82 (0.43-1.54) 0.53
> 30 48.15 ± 5.51 1
Sex of donor - recipient F-F 47.70 ± 7.11 1.35 (0.58-3.14) 0.48
F-M 59.45 ± 9.21 0.91 (0.36-2.32) 0.85
M-F 42.27 ± 6.37 1.18 (0.51-2.73) 0.70
M-M 57.3 ± 8.28 1
AML M3 20.55 ± 7.49 1.15(0.28-4.76) 0.84
Non-M3 54.00 ± 4.58 1
Different types of ALM M2 34.62 ± 9.11 10.3 (0.13-0.68) 0.04* 0.56 (0.21-1.49) 0.25
M4 61.24 ± 6.43 1 1
M5 56.66 ± 7.89 0.51 (0.23-1.10) 0.09 0.72 (0.32-1.61) 0.42

Acute graft-versus-host diseases (aGVHD), chronic graft-versus-host diseases (cGVHD), first and second complete remission (CR1, CR2)