Table 3.
Prevalence of bacterial genera amongst cases and controls sorted according to total prevalence in the subsample
Genus | Case prevalence (%) | Control prevalence (%) | HR | Confidence interval 95% | p-value |
---|---|---|---|---|---|
Streptococcus | 42.3 | 58.9 | 0.54 | 0.36–0.81 | 0.003 |
Staphylococcus | 38.3 | 25.1 | 1.70 | 1.09–2.57 | 0.020 |
Enhydrobacter* | 34.8 | 13.1 | 3.30 | 2.01–5.57 | < 0.001 |
Kocuria* | 22.5 | 3.4 | 8.50 | 4.05–17.84 | < 0.001 |
Paracoccus* | 5.7 | 18.3 | 0.29 | 0.15–0.57 | < 0.001 |
Stenotrophomonas | 7.5 | 13.7 | 0.48 | 0.25–0.92 | 0.028 |
Veillonella | 4.9 | 12.0 | 0.32 | 0.15–0.68 | 0.003 |
Bacteroides | 2.6 | 10.9 | 0.24 | 0.09–0.63 | 0.004 |
Hazard ratios for cardiovascular disease mortality by Cox proportional hazard regression univariate analyses are presented with accompanying confidence intervals and p-values for the bacteria found to be significant at the 2% cut-off point. Each genus must be present in at least five cases and five controls as well as over five per cent total prevalence to be included in the analyses
*The bacterial genus is also significant when considering the Bonferroni correction