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. Author manuscript; available in PMC: 2022 Jul 31.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2020 Dec 23;110(1):11–20. doi: 10.1016/j.ijrobp.2020.11.020

Figure 2.

Figure 2.

Probability of Grade 2 or higher toxicity as a function of mean lung dose. Horizontal error bars on data points are standard deviation for MLD for patients in a particular MLD bin; vertical error bars are 68% binomial CI for the observed outcome. Solid line shows the logistic curve, dashed and dotted lines are confidence intervals calculated using bootstrap (68% dashed, 95% dotted). Bin size was set to 1 Gy to obtain sufficient resolution to visualize MLD-response while keeping MLD variance within the bin reasonably small.