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Gpdh1 mutant females are short-lived. The lifespan of a) females and b) males from Gpdh1A10/+ heterozygous controls, F1 generation Gpdh1A10 mutants, and a Gpdh1A10 M/Z mutant strain were analyzed for 80 days after eclosion. Longevity data were analyzed using a log-rank (Mantel–Cox) test. c) Ratio of males to females in culture bottles either 2 or 14 days after eclosion. *P < 0.05. P-values calculated using an unpaired t-test.
