Table III.

Hazard of Mortality by Cox Proportional Hazard Modeling

	Hazard Ratio (95% CI)1	P value
Age at Diagnosis	1.02 (1.02, 1.02)	<0.001
Race
White	Reference
Black	1.03 (0.99, 1.07)	0.1113
Asian or Pacific Islander	0.65 (0.61, 0.69)	<0.001
Other, Unknown	0.76 (0.69, 0.83)	<0.001
Spanish/Hispanic Origin
Non-Spanish, Non-Hispanic	Reference
Spanish, Hispanic	0.78 (0.74, 0.81)	<0.001
Unknown	1.06 (1.00, 1.12)	0.0396
Primary Payor
Not Insured	Reference
Private Insurance/Managed Care	0.82 (0.76, 0.90)	<0.001
Medicaid	0.98 (0.89, 1.08)	0.7417
Medicare	1.22 (1.13, 1.33)	<0.001
Other Government	1.11 (0.97, 1.28)	0.1217
Insurance Status Unknown	0.93 (0.83, 1.04)	0.2149
Charlson-Deyo Score
0	Reference
1	1.14 (1.11, 1.18)	<0.001
2	1.38 (1.32, 1.45)	<0.001
≥ 3	1.56 (1.46, 1.67)	<0.001
Urban/Rural
Metro Area	Reference
Adjacent to Metro Area	1.06 (1.02, 1.11)	0.0054
Not Adjacent to Metro Area	1.10 (1.03, 1.17)	0.0025
Median Income Quartiles 2008–2012
< $38,000	Reference
$38,000–$47,999	0.99 (0.95, 1.03)	0.5690
$48,000–$62,999	0.94 (0.91, 0.98)	0.0029
>=$63,000	0.88 (0.85, 0.91)	<0.001
NCDB Analytic Stage Group
Stage 0	Reference
Stage I	1.28 (1.17, 1.39)	<0.001
Stage II	1.86 (1.71, 2.04)	<0.001
Stage III	2.81 (2.58, 3.07)	<0.001
Grade
Well differentiated, differentiated, NOS	Reference
Moderately differentiated	1.46 (1.36, 1.56)	<0.001
Poorly differentiated	1.88 (1.76, 2.00)	<0.001
Undifferentiated, anaplastic	1.85 (1.64, 2.08)	<0.001
Cell type not determined	1.70 (1.58, 1.82)	<0.001
Guideline Adherence
Primary Treatment not per NCCN Guidelines	Reference
Primary Treatment per NCCN Guidelines	0.63 (0.61, 0.65)	<0.001
Year of Diagnosis
2004 – 2006	Reference
2007 – 2009	1.04 (1.00, 1.08)	0.0377
2010 – 2015	0.98 (0.95, 1.01)	0.1623

¹Adjusted for selected factor and hospital adherence rate