Acquisition scheme for 5D D-R2 distribution MRI. Images are recorded as a function of the magnitude b, normalized anisotropy bΔ (defined in Eq. (3)) and orientation (Θ,Φ) of the b-tensor, as well as the echo time τE at constant repetition time τR of 5 s. All panels share the same abscissa, where nacq is the acquisition number sorted in the order of ascending τE, b, and bΔ.