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. Author manuscript; available in PMC: 2023 Jan 20.
Published in final edited form as: Nature. 2022 Jul 20;607(7920):769–775. doi: 10.1038/s41586-022-04896-7

Extended Data 11: Pathologic analysis of Mlkl−/−::Casp8−/−::Adarp150null/P195A mice.

Extended Data 11:

A-B. Immunohistochemical staining (A) and quantification (B) in liver for cleaved-caspase 3. (n=3 d.0 pups, each group) Original magnification 10x. C. Additional histological images of other tissue sites (kidney, liver and small intestine). Kidney (20x) and liver (10x) PAS staining, small intestine HE staining (original magnification as stated). D-E. Immunohistochemical staining, with 2.5x and 10x images (D) and quantification (E) in brain for Iba1 (n=3 d.0 pups, each group). B & E use tissues from matched animals.