Table 2.
Arm | PFS6 | ORR (measurable only) |
mPFS | mOS | mPFS (non-BRCA or PALB2) |
mOS (non-BRCA or PALB2) |
mPFS (no DDR variant) |
mOS (no DDR variant) |
---|---|---|---|---|---|---|---|---|
% (95% CI) | Mo (95% CI) | |||||||
Nira/Nivo | N = 44 | N = 42 | N = 44 | N = 44 | N = 37 | N = 37 | N = 32 | N = 32 |
Nira/Ipi | N = 40 | N = 39 | N = 40 | N = 40 | N = 33 | N = 33 | N = 30 | N = 30 |
Nira/Nivo |
20.6 (8.3-32.9)
p=0.0002 vs 44% |
7.1 (1.5-19.5) | 1.9 (1.4-2.3) | 13.2 (8.1-16.7) | 1.9 (1.8-1.9) | 13.2 (8.1-16.7) | 1.8 (1.8-1.9) | 13.2 (6.1-20.3) |
Nira/Ipi |
59.6 (44.3-74.9)
p=0.045 vs 44% |
15.4 (5.9-30.5) | 8.1 (5.5-10.6) | 17.3 (12.8-21.9) | 7.6 (4.0-11.1) | 17.3 (12.5-22.2) | 7.6 (2.8-12.3) | 15.0 (4.3-25.7) |
Italics indicate lack of overlap between CIs