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. Author manuscript; available in PMC: 2023 Jul 25.
Published in final edited form as: Dev Cell. 2022 Jul 8;57(14):1776–1788.e8. doi: 10.1016/j.devcel.2022.06.010

Figure 4. Mutations in condensate-promoting features cause diverse condensate dysregulation phenotypes.

Figure 4.

Models for observed types of condensate dysregulation resulting from pathogenic mutations that affect condensate-promoting features of condensate-forming proteins, including altered condensate incorporation (left), enhanced condensate formation (middle), and altered condensate localization (right). Candidate where these phenotypes were observed (Figure 3C) are listed.