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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Alzheimers Dement. 2022 Feb 1;18(11):2272–2282. doi: 10.1002/alz.12552

Figure 1. Relations between cortical amyloid burden, markers of neurodegeneration and memory performance in male and female PSEN1 mutation carriers and non-carriers.

Figure 1.

Note. A, FDG precuneus as a function of amyloid burden. B, Hippocampal volume as a function of amyloid burden. C, Word list delayed recall as a function of FDG precuneus. D, Word list delayed recall as a function of hippocampal volume. Orange represents females and green represents males. Top row depicts PSEN1 mutation carriers, bottom row depicts non-carriers. Abbreviations: Amyloid Burden, mean cortical florbetapir standard uptake value ratios (SUVRs); FDG Precuneus, glucose metabolism in the precuneus relative to the whole brain; Hippocampal Volume, Hippocampal to total intracranial volume ratios.