Table 1:
Baseline demographics and medical history.
| MBI− (N=8607) |
MBI+ (N=2765) |
Test statistic (t-stat or X2 stat) |
p-value | |
|---|---|---|---|---|
| Demographics (mean (SD) or N(%)) | ||||
| Age | 70.6 (10.4) | 70.1 (10.3) | 2.2 | .03 |
| MMSE | 29.0 (1.4) | 28.8 (1.5) | 3.8 | <.001 |
| Education (yrs) | 15.9 (2.9) | 15.6 (3.1) | 4.8 | <.001 |
| Sex (male) | 2828 (33%) | 1092 (40%) | 40.8 | <.001 |
| Medications (use versus no use) N(%)) | ||||
| Anxiolytic | 834 (10%) | 434 (16%) | 76.2 | <.001 |
| Antidepressant | 1264 (15%) | 818 (30%) | 310.6 | <.001 |
| Antipsychotic | 34 (.4%) | 27 (1%) | 13.3 | <.001 |
| Medical Conditions (presence versus absence) (N(%)) | ||||
| Diabetes | 840 (10%) | 333 (12%) | 11.9 | .001 |
| Hypercholesterolemia | 3801 (46%) | 1353 (51%) | 20.9 | <.001 |
| Hypertension | 3736 (45%) | 1297 (48%) | 12.2 | <.001 |
| Heart attack | 58 (.7%) | 24 (1%) | 1.2 | .28 |
| Atrial Fibrillation | 333 (4%) | 142 (5%) | 8.3 | .004 |
| Stroke | 38 (.4%) | 18 (.7%) | 1.9 | .16 |
| TIA | 88 (1%) | 28 (1%) | 0 | .99 |
| Health Behaviours (mean (SD) or N(%)) | ||||
| Smoking (years) | 8.7 (13.8) | 10.1 (15.0) | −4.5 | <.001 |
| Alcohol abuse (past or present) | 29 (.3%) | 20 (.8%) | 7.8 | .01 |
| Other Risk Factors | ||||
| APOE4 allele (presence versus absence) | 2339 (31%) | 767 (32%) | 1.6 | .20 |