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The effects of LAMA2 c.8842G > A mutation on the molecular structure of the protein. (A) Individual crystal structures of wild type and G2948S according to the 1okq.1.A model template. (B) Ramachandran plots of amino acid with wild type and p.G2948A. (C) The comparisons of free energy on crystal structure of the wild type sequence and the p.G2948A variant. (D) The structural changes due to the mutation of LAMA2 G2948S.
