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. 2022 Jul 18;12:937481. doi: 10.3389/fcimb.2022.937481

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Copyright © 2022 Sharma, Kumar, Rauf, Chaudhary, Prajapati, Emran, Gonçalves Lima and Conte-Junior

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Major risk factors in CAM. Fungal infections typically occur due to a compromised immune status. Several factors such as diabetes, iron metabolism, COVID-19 treatments, steroid therapy, organ transplants, and certain cancers represent the major risk factors for mucormycosis. Apart from these, fungal spore burden, prevalence of diabetes, zinc supplements, and hospital environment might also contribute to mucormycosis cases post-COVID-19. COVID-19, Coronavirus disease 2019; GRP-78, glucose-regulated protein 78; CAM, COVID-19 associated mucormycosis; GIDM, Glucocorticoid-Induced Diabetes Mellitus; ICU, Intensive Care Unit.