Fig. 2.

Network of DNA damage-, DNA repair- and checkpoint control-related genes affected in rat liver by CTD, as obtained from previously published data (Alarcan et al., 2021) using IPA software. Continuous lines indicate direct functional relationships, dashed lines indicate indirect connections. Network nodes are labeled with the gene name and the functional classification of genes is denoted by their different shapes. Additional nodes were added to the network manually based on literature (Bonner et al., 2008; Hauer and Gasser, 2017; Hustedt and Durocher, 2016; Panier and Boulton, 2014; Polo and Jackson, 2011).