TABLE 1.

Two-sample Mendelian randomization (MR) analyses of the association between dried fruit intake and eleven site-specific cancers.

Outcome	IVW method			WM method
	OR	95% CI of OR	P-value	OR	95% CI of OR	P-value
Oral cavity and pharyngeal cancer	0.1732	(0.0433, 0.6922)	0.0131*	0.2656	(0.0379, 1.8616)	0.1821
Lung cancer	0.3299	(0.1695, 0.6420)	0.0011*	0.3597	(0.1585, 0.8160)	0.0144*
Squamous cell lung cancer	0.2300	(0.0884, 0.5986)	0.0026*	0.1794	(0.0550, 0.5848)	0.0044*
Breast cancer	0.4693	(0.3261, 0.6753)	4.62 × 10–5*	0.3520	(0.2247, 0.5512)	5.04 × 10–6*
Ovarian cancer	0.6028	(0.3960, 0.9177)	0.0183*	0.7575	(0.4363, 1.3153)	0.3239
Pancreatic cancer	0.0274	(0.0011, 0.6784)	0.0280*	0.0128	(0.0002, 0.9969)	0.0498*
Cervical cancer	0.9947	(0.9897,0.9998)	0.0428*	0.3045	(0.1731, 1.7297)	0.3045
Lung adenocarcinoma	0.7079	(0.2976, 1.6831)	0.4342	1.2855	(0.6510, 2.5385)	0.4694
Endometrial cancer	0.9586	(0.5679, 1.6180)	0.8742	0.1525	(3.32 × 10–5, 699.9797)	0.6620
Thyroid cancer	0.1854	(0.0001, 195.8003)	0.6352	1.3370	(0.9383, 1.9048)	0.1080
Prostate cancer	1.1424	(0.7498, 1.7406)	0.5354	1.3370	(0.9383, 1.9048)	0.1080
Bladder cancer	1.0003	(0.9956,1.0050)	0.8996	1.0013	(0.9953,1.0073)	0.6756
Brain cancer	1.0003	(0.9972,1.0035)	0.8164	1.0003	(0.9961,1.0045)	0.8786

OR, odds ratios; 95% CI, 95% confidence interval; IVW, inverse-variance-weighted; WM, weighted median.

*Indicate P < 0.05. The bold values represent the statistically significant P-values.