Table 1. Baseline characteristics .
All patients (N=264) | PTMC group (N=164) | MVR group (N=100) | P value | |
Mean age, years | 49.52 ± 13.03 | 47.38 ± 13.38 | 53.04 ± 11.69 | 0.001 |
Female, (%) | 213 (80.7%) | 131 (79.9%) | 82 (82%) | 0.672 |
Atrial fibrillation, (%) | 181 (68.6%) | 87 (53%) | 94 (94%) | < 0.001 |
Comorbidity, (%) | ||||
Type 2 diabetes mellitus | 27 (10.2%) | 18 (11%) | 9 (9%) | 0.626 |
Hypertension | 38 (14.4%) | 24 (14.6%) | 14 (14%) | 0.912 |
Dyslipidemia | 18 (6.8%) | 9 (5.5%) | 9 (9%) | 0.262 |
Chronic kidney disease, (GFR < 60 ml/min/1.73 m2) |
5 (1.9%) | 4 (2.4%) | 1 (1%) | 0.653 |
Indication, (%) | ||||
Dyspnea | 134 (50.8%) | 84 (51.2%) | 50 (50%) | 0.897 |
Heart failure | 98 (37.1%) | 56 (34.1%) | 42 (42%) | 0.181 |
Stroke and systemic embolism | 30 (11.4%) | 18 (11%) | 12 (12%) | 0.782 |
New onset atrial fibrillation | 38 (14.4%) | 29 (17.7%) | 9 (9%) | 0.054 |
SPAP > 50 mmHg | 8 (3%) | 6 (3.7%) | 2 (2%) | 0.714 |
Planned pregnancy or major surgery | 9 (3.4%) | 9 (5.5%) | 0 (0%) | 0.018 |
Preprocedural Echocardiographic data | ||||
Wilkins’ score | 8.59 ± 1.85 | 8.10 ± 1.56 | 9.47 ± 2.01 | < 0.001 |
Wilkins’ score ≥ 8, (%) | 192 (72.7%) | 112 (68.3%) | 80 (80%) | < 0.001 |
MVA by planimetry, cm2 | 0.91 ± 0.30 | 0.94 ± 0.27 | 0.85 ± 0.32 | 0.016 |
MVA by PHT, cm2 | 0.96 ± 0.28 | 0.98 ± 0.26 | 0.89 ± 0.27 | 0.005 |
Mean PG, mmHg | 12.67 ± 5.81 | 12.74 ± 6.11 | 12.56 ± 5.5 | 0.823 |
RVSP, mmHg | 54.77 ± 22.77 | 54.19 ± 23.10 | 55.70 ± 21.23 | 0.631 |
Mean PAP, mmHg | 32.83 ± 12.00 | 34.48 ± 13.50 | 31.58 ± 11.27 | 0.269 |
Follow up time*,month | 62.0 (28.0, 102.0) |
62.5 (27.25, 101.0) |
57.0 (28.25, 102.75) |
0.966 |
* Median with interquartile range
GFR = Glomerular filtration rate, MVA = Mitral valve area, MVR = Mitral valve replacement, PAP = Pulmonary arterial pressure, PHT = Pressure-half time, PG = pressure gradient, PTMC = Percutaneous mitral commissurotomy, RVSP = Right ventricular systolic pressure, SPAP = Systolic pulmonary arterial pressure.