Table 2. Outcomes of PTMC and MVR groups .
|
PTMC group
(N,164) |
MVR group
(N,100) |
P value | |
| Primary outcome: all-causedeath; stroke or systemic embolism; heart failure hospitalization and re-intervention; (%) | 61 (37.2%) | 22 (22%) | 0.002 |
| All-causes mortality;(%) | 28 (17.1%) | 15 (15%) | 0.658 |
| Stroke or systemic embolism; (%) | 7 (4.3%) | 5 (5%) | 0.963 |
| Heart failure hospitalization; (%) | 19 (11.6%) | 7 (7%) | 0.101 |
| Re-intervention; (%) | 30 (18.3%) | 0 (0%) | < 0.001 |
| Periprocedural complication; (%) | 14 (8.5%) | 16 (16%) | N/A |
| Cardiac tamponade | 5 (3%) | 0 | |
| Severe MR | 8 (4.9%) | 0 | |
| Re-sternotomy | N/A | 4 (4%) | |
| AKI required dialysis | 0 | 4 (4%) | |
| Complete heart block | |||
| - Temporary pacemaker | 0 | 3 (3%) | |
| - Permanent pacemaker | 0 | 1 (1%) | |
| Death | 1 (0.6%) | 4 (4%) | |
| Valvular infection; (%) | 2 (1.2%) | 5 (5%) | 0.911 |
| Bleeding; (%) | 14 (8.5%) | 12 (12%) | |
| Severity (according to BARC definition) | |||
| - Non serious bleeding (BARC < 3) | 11 (6.7%) | 5 (5%) | Reference |
| - Serious bleeding (BARC ≥ 3) | 3 (1.8%) | 7 (7%) | 0.062 |
| Site of serious bleeding | |||
| - Intracranial hemorrhage | 1 (0.6%) | 4 (4%) | |
| - GI tract bleeding | 2 (1.2%) | 0 | |
| - Joint and muscle bleeding | 0 | 2 (2%) | |
| - Others | 0 | 1 (1%) | |
| Length of hospital stays*; days | 1 (1; 2) | 9 (9; 16) | < 0.001 |
Abbreviations: AKI, Acute kidney injury; BARC , Bleeding Academic Research Consortium; MR , Mitral regurgitation; MVR , Mitral valve replacement; PTMC , Percutaneous mitral commissurotomy.
*Median with interquartile range