TABLE 2.

Phenotype of candidate pathogenic genes in MGI database.

Gene	Human phenotypes	Mouse genotype
CASQ2	Ventricular tachycardia	Ventricular tachycardia
	Syncope	Abnormal sinus arrhythmia
	Bradycardia	Abnormal cardiac muscle relaxation
ANK2	Atrial fibrillation	Increased heart rate variability
	Sudden cardiac death	Abnormal sinoatrial node conduction
	Sinus bradycardia	None
	Syncope	None
SYNE2	Arrhythmia	Abnormal retinal blood vessel morphology
	Cardiomyopathy	None
GJD3	None	Abnormal impulse conducting system conduction
	None	Abnormal atrioventricular node conduction
	None	Shortened PQ interval
NOS1	None	Increased heart rate
	None	Acardiac muscle relaxation
RYR2	Ventricular arrhythmia	Ventricular tachycardia
	Ventricular tachycardia	Increased heart rate
COL4A3	Hypertension	Abnormal glomerular capillary morphology
LAMC1	None	Intracranial hemorrhage
TRDN	Ventricular tachycardia	None
ANO6	None	Shortened PQ interval