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. 2022 Jul 26;17:3217–3237. doi: 10.2147/IJN.S364264

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© 2022 Zheng et al.

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The mechanism behind synergistic therapeutic efficacy of FCNPIFE. (A) PA images of different groups in oxy-hemoglobin mode before/post-irradiation (1.5W/cm²,10 min). (B) Quantification of oxyhemoglobin saturation in tumor regions of different groups (n =3, ****p < 0.0001). (C) HIF-1α immunofluorescent staining of tumors collected from different groups on the 1st day post-treatments. (D) HSP70 immunofluorescent staining of tumors collected from different groups on the 1st day post-treatments. (E) Quantitative analysis of HSP70 expression of different groups on the 1st day post-treatment (n =3, **p < 0.01).