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. 2022 Mar 2;77(8):805–811. doi: 10.1136/thoraxjnl-2021-218196

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Change in secondary outcomes (MIC−VC (L), PCF-assisted – PCF-unassisted (L/min), MIP (cm H₂O), MEP (cm H₂O) and TLC (L) over time. Marginal means by group with 95% CI from mixed effect model of secondary outcomes, adjusted for age and ambulatory status, at 6-month intervals. MEP, maximal expiratory pressure; MIC, maximum insufflation capacity; MIP, maximal inspiratory pressure; PCF, peak cough flow; TLC, total lung capacity.