Table 5.

Logistic regression analysis for predicting the likelihood of patients requiring additional topical steroids while being treated with topical ciclosporin/Ikervis (total n=387 patients). Patients who were intolerant to the Ikervis were excluded from this analysis

Parameters	OR (95% CI)	P value
Age, years		0.04
0–18	0.62 (0.12 to 3.19)	0.56
>18 to 30	3.02 (0.86 to 10.61)	0.09
>31 to 50	0.44 (0.13 to 1.55)	0.2
>51 to 70	1.59 (0.64 to 3.94)	0.32
>70	Reference	–
Gender
Female	0.78 (0.37 to 1.65)	0.52
Male	Reference	–
Indications		<0.001
Dry eye disease	Reference	–
AED	9.18 (3.01 to 27.94)	<0.001
OMMP/SJS	0.90 (0.19 to 4.18)	0.89
Post-keratoplasty	9.59 (2.66 to 34.57)	0.001
Others	1.27 (0.34 to 4.78)	0.72
Treatment frequency		0.016
Once a day	Reference	–
Twice a day	2.86 (1.39 to 5.90)	0.04
>Twice a day	3.19 (0.29 to 35.25)	0.34

AED, allergic eye disease (which included vernal keratoconjunctivitis and atopic keratoconjunctivitis; OMMP, ocular mucous membrane pemphigoid; SJS, Steven-Johnson syndrome.