Table 4.
Predictors for 1-year target lesion failure
| Univariable | Multivariable | ||||||
| Predictor | OR | 95% CI | P value | OR | 95% CI | P value | |
| Region | |||||||
| Europe vs Asia | 1.63 | 1.36 to 1.96 | <0.0001 | Europe vs Asia | 1.56 | 1.29 to 1.89 | <0.0001 |
| Europe vs Africa/Middle East | 1.80 | 1.31 to 2.47 | 0.0003 | Europe vs Africa/Middle East | 2.01 | 1.45 to 2.79 | <0.0001 |
| Europe vs South America/Mexico | 0.84 | 0.67 to 1.05 | 0.13 | Europe vs South America/Mexico | 0.91 | 0.72 to 1.14 | 0.39 |
| Clinical | |||||||
| Age (+10 years) | 1.33 | 1.27 to 1.41 | <0.0001 | Age (+10 years) | 1.17 | 1.10 to 1.24 | <0.0001 |
| Body mass index (+5 kg/m²) | 0.95 | 0.89 to 1.02 | 0.17 | Body mass index (+5 kg/m²) | 0.93 | 0.87 to 1.01 | 0.073 |
| Diabetes | 1.62 | 1.43 to 1.83 | <0.0001 | Diabetes | 1.44 | 1.26 to 1.64 | <0.0001 |
| Renal impairment | 2.77 | 2.36 to 3.26 | <0.0001 | Renal impairment | 1.92 | 1.62 to 2.29 | <0.0001 |
| Previous PCI | 1.68 | 1.48 to 1.90 | <0.0001 | Previous PCI | 1.42 | 1.23 to 1.63 | <0.0001 |
| Previous CABG | 2.55 | 2.12 to 3.07 | <0.0001 | Previous CABG | 1.30 | 1.03 to 1.65 | 0.027 |
| NSTE-ACS | 1.13 | 1.00 to 1.28 | 0.049 | NSTE-ACS | 1.20 | 1.05 to 1.38 | 0.0093 |
| STEMI | 1.04 | 0.90 to 1.21 | 0.57 | STEMI | 1.58 | 1.33 to 1.87 | <0.0001 |
| Multivessel disease | 1.67 | 1.48 to 1.89 | <0.0001 | ||||
| Lesion/procedural | |||||||
| No of lesions identified (+1) | 1.33 | 1.27 to 1.39 | <0.0001 | No of lesions identified (+1) | 1.24 | 1.17 to 1.31 | <0.0001 |
| No of lesions treated (+1) | 1.30 | 1.19 to 1.41 | <0.0001 | No of lesions treated (+1) | 0.81 | 0.70 to 0.93 | 0.0022 |
| RCA treated | 0.74 | 0.65 to 0.84 | <0.0001 | RCA treated | 0.73 | 0.64 to 0.84 | <0.0001 |
| Left main treated | 3.38 | 2.75 to 4.17 | <0.0001 | Left main treated | 1.88 | 1.49 to 2.38 | <0.0001 |
| Graft treated | 4.03 | 3.00 to 5.46 | <0.0001 | Graft treated | 1.83 | 1.26 to 2.66 | 0.0016 |
| Bifurcation | 1.77 | 1.52 to 2.06 | <0.0001 | Bifurcation | 1.32 | 1.12 to 1.56 | 0.0011 |
| In-stent restenosis | 1.73 | 1.40 to 2.04 | <0.0001 | In-stent restenosis | 1.24 | 0.98 to 1.57 | 0.068 |
| Moderate/severe calcification | 1.50 | 1.31 to 1.71 | <0.0001 | ||||
| Lesion type B2 | 1.38 | 1.21 to 1.57 | <0.0001 | ||||
| Lesion type C | 1.43 | 1.25 to 1.62 | <0.0001 | ||||
| Small vessels | 1.23 | 1.10 to 1.39 | 0.0005 | ||||
| Total stent length | 1.008 | 1.006 to 1.011 | <0.0001 | ||||
| No of stents implanted (+1) | 1.30 | 1.23 to 1.37 | <0.0001 | No of stents implanted (+1) | 1.26 | 1.15 to 1.37 | <0.0001 |
| Radial access | 0.73 | 0.64 to 0.85 | <0.0001 | Radial access | 0.81 | 0.69 to 0.94 | 0.0066 |
CABG, coronary artery bypass graft; NSTE-ACS, non-ST-segment elevation acute coronary syndrome; PCI, percutaneous coronary intervention; RCA, right coronary artery; STEMI, ST-segment elevation myocardial infarction.