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. 2021 Aug 18;26(5):1056–1069. doi: 10.1177/13623613211039673

Table 3.

Items that met criteria for adequate distinction between MAD and ASD.

ADOS Items Module 3 MAD
n (%)
ASD
n (%)
Communication domain
 Speech abnormalities associated with autism 44 (25.6) 298 (76.7)
 Reporting of events a 53 (30.8) 295 (77.2)
 Conversation a 51 (29.7) 323 (83.3)
Reciprocal social interaction domain
 Facial expressions directed to examiner a 50 (29.1) 330 (85.1)
 Quality of social overtures a 41 (23.8) 341 (87.9)
 Quality of social response a 56 (32.6) 301 (77.6)
ADOS Items Module 4 MAD
n (%)
ASD
n (%)
Communication domain
 Conversation a 25 (28.1) 143 (72.2)
 Descriptive, conventional, instrumental, or informational gestures a 25 (28.1) 145 (73.2)
Reciprocal social interaction domain
 Insightb 29 (32.6) 160 (80.8)
 Quality of social overtures a 19 (21.4) 146 (73.7)
 Quality of social response a 23 (25.8) 144 (72.7)
Restricted repetitive behaviors
 Speech abnormalities associated with autism b 28 (31.5) 136 (68.7)

N = 847. Module 3: n = 560. Module 4: n = 287. Items met criteria for adequate distinction between groups if they were endorsed in >66% of ASD and <33% of MAD. MAD: mood and anxiety disorder; ASD: autism spectrum disorder; ADOS: Autism Diagnostic Observation Schedule.

a

Algorithm items of ADOS-2. bNot included in ADOS but in ADOS-2 in Module 4.