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. 2022 Jul 18;9:844618. doi: 10.3389/fmolb.2022.844618

TABLE 2.

ONCOMINE analyses indicating significant differences in mRNA expression of HMGB family members between lung cancer and normal lung tissue.

Type of lung cancer vs. normal Fold change p-value t-test References
HMGB2 Squamous Cell Lung Carcinoma vs. Normal 2.698 0.003 2.895 Bhattacharjee et al. (2001)
HMGB3 Lung Adenocarcinoma vs. Normal 4.651 2.08e-25 15.357 Landi et al. (2008)
Lung Adenocarcinoma vs. Normal 3.721 5.19e-10 8.603 Su et al. (2007)
Lung Adenocarcinoma vs. Normal 4.543 4.59e-21 16.016 Okayama et al. (2012)
Lung Adenocarcinoma vs. Normal 5.974 3.38e-15 10.682 Hou et al. (2010)
Squamous Cell Lung Carcinoma vs. Normal 4.877 6.71e-17 13.624 Hou et al. (2010)
Large Cell Lung Carcinoma vs. Normal 6.378 1.91e-7 7.445 Hou et al. (2010)
Lung Adenocarcinoma vs. Normal 4.203 5.18e-4 3.819 Bhattacharjee et al. (2001)
Squamous Cell Lung Carcinoma vs. Normal 3.672 3.31e-4 7.858 Wachi et al. (2005)
Lung Adenocarcinoma vs. Normal 4.367 5.58e-16 10.385 Selamat et al. (2012)