TABLE 4.

The Spearman correlation R value and p-value of HMGB family members with infiltrating immune cells in NSCLC samples.

Immune cell	Spearman correlation R			p- value
	HMGB1	HMGB2	HMGB3	HMGB1	HMGB2	HMGB3
aDC	−0.078	0.060	−0.061	0.011	0.054	0.051
B cells	−0.031	−0.038	−0.052	0.321	0.219	0.097
CD8 T cells	−0.216	−0.174	0.139	<0.001	<0.001	<0.001
Cytotoxic cells	−0.024	−.043	−0.033	0.436	0.168	0.291
DC	−0.223	−0.290	−0.126	<0.001	<0.001	<0.001
Eosinophils	−0.298	−0.346	0.031	<0.001	<0.001	0.317
iDC	−0.242	−0.336	−0.135	<0.001	<0.001	<0.001
Macrophages	−0.240	−0.289	−0.087	<0.001	<0.001	0.005
Mast cells	−0.262	−0.449	−0.054	<0.001	<0.001	0.081
Neutrophils	−0.237	−0.313	−0.136	<0.001	<0.001	<0.001
NK CD56bright cells	−0.252	−0.116	0.191	<0.001	<0.001	<0.001
NK CD56dim cells	−0.002	0.166	−0.064	0.959	<0.001	0.041
NK cells	−0.247	−0.150	−0.123	<0.001	<0.001	<0.001
pDC	−0.254	−0.191	−0.020	<0.001	<0.001	0.528
T cells	−0.031	−0.005	−0.078	0.318	0.870	0.012
T helper cells	0.020	0.076	0.105	0.530	0.014	<0.001
Tcm	−0.010	−0.019	−0.099	0.747	0.531	0.001
Tem	−0.234	−0.130	0.088	<0.001	<0.001	0.005
TFH	−0.260	−0.185	0.143	<0.001	<0.001	<0.001
Tgd	0.088	0.087	−0.049	0.005	0.005	0.118
Th1 cells	−0.158	−0.136	−0.095	<0.001	<0.001	0.002
Th17 cells	−0.286	−0.254	0.222	<0.001	<0.001	<0.001
Th2 cells	0.256	0.509	0.098	<0.001	<0.001	0.002
TReg	−0.079	0.093	−0.094	0.011	0.003	0.002