Table 2. Predictive Performance of Three Models in the Training and Validation Cohorts.

Model	Training Cohort (n = 311)			Validation Cohort (n = 211)
	AUC (95% CI)	Sensitivity*	Specificity*	AUC (95% CI)	Sensitivity*	Specificity*
Radiomics model	0.767 (0.709–0.825)	0.750	0.659	0.784 (0.712–0.855)	0.750	0.695
Clinical model	0.823 (0.775–0.871)	0.705	0.789	0.844 (0.788–0.900)	0.717	0.788
Clinical-radiomics model	0.868 (0.825–0.910)	0.739	0.861	0.890 (0.844–0.936)	0.817	0.841

^*Balanced sensitivity and specificity at the cutoff yielding the largest Youden index value. AUC = area under the receiver operating characteristic curve, CI = confidence interval