Table 3.
Statistical evaluation of SICTT using real-time PCR and immunohistochemistry (IHC). Data are presented as percentage
Type | Method | Sensitivity | Specificity | Accuracy | Prevalence | PPV 4 | NPV 5 | Kappa ( p < 0.0005) |
---|---|---|---|---|---|---|---|---|
M. bovis 1 | Real-time PCR | 53.70 | 100 | 63.80 | 78.26 | 100 | 37.50 | 0.34 |
IHC | 53.70 | 100 | 63.80 | 78.26 | 100 | 100 | 0.34 | |
MTC 2 | Real-time PCR | 100 | 100 | 100 | 8.00 | 100 | 100 | 1.00 |
IHC | 100 | 100 | 100 | 8.00 | 100 | 100 | 1.00 | |
MAP 3 | Real-time PCR | 60.50 | 100 | 78.30 | 55.00 | 100 | 67.40 | 0.58 |
IHC | 60.50 | 93.60 | 75.40 | 55.00 | 92.00 | 65.90 | 0.52 |
1 Mycobacterium bovis; 2 Mycobacterium tuberculosis complex; 3 Mycobacterium avium subsp. paratuberculosis; 4 Positive predictive values; and 5 Negative predictive values.