Table 3.

Regression results of testing the effect of PRS for serum testosterone and total surface area in females

Predictors	Estimates	SE	Std. Beta	Standardized SE	Standardized CI	Statistic	P  *	Number of SNPs
Main effect
5*10−8	1127320.85	892343.65	0.02	0.02	−0.01—0.06	1.26	0.206	84
0.001	−354207.1	8332570.19	0	0.02	−0.04—0.03	−0.04	0.966	1917
0.01	−50 883 254	22447030.5	−0.04	0.02	−0.08—−0.01	−2.27	0.023 *	9808
0.05	−105 906 398	44735865.3	−0.04	0.02	−0.08—−0.01	−2.37	0.018 *	32 467
0.5	−367 182 317	141 164 366	−0.05	0.02	−0.08—−0.01	−2.6	0.009 *	164 249
1	−477 743 843	191 461 063	−0.05	0.02	−0.08 – −0.01	−2.5	0.013 *	230 215
Interaction with age (linear term)
5*10−8	35106253.42	9758461.83	0.7	0.19	0.32–1.08	3.6	<0.001 * *	84
0.001	46762013.06	104 969 673	0.1	0.22	−0.33– 0.52	0.45	0.656	1917
0.01	−465 262 904	277 494 893	−0.36	0.22	−0.79– 0.06	−1.68	0.094	9808
0.05	−1 141 413 442	507 680 927	−0.44	0.2	−0.83 – −0.06	−2.25	0.025 *	32 467
0.5	−4 795 299 290	1 615 227 570	−0.59	0.2	−0.98 – −0.20	−2.97	0.003 *	164 249
1	−6 190 370 444	2 179 198 099	−0.57	0.2	−0.96 – −0.17	−2.84	0.005 *	230 215
Interaction with age (quadratic term)
5*10−8	296415.22	9193904.88	0.01	0.19	−0.36– 0.37	0.03	0.974	84
0.001	13222079.3	92336579.3	0.03	0.19	−0.35– 0.40	0.14	0.886	1917
0.01	−97 506 765	235 388 392	−0.08	0.19	−0.44– 0.29	−0.41	0.679	9808
0.05	402739260.5	477 674 540	0.16	0.19	−0.21– 0.53	0.84	0.399	32 467
0.5	1 584 337 524	1 497 253 898	0.2	0.19	−0.17– 0.56	1.06	0.29	164 249
1	2 113 042 144	2 026 616 501	0.2	0.19	−0.17– 0.56	1.04	0.297	230 215
N	188id
	153twinid
Observations	343

^* P value <0.05 “*” and <0.002 “**” (P value for significance after correction for multiple comparison).