Figure 3.

Gut stiffness index predicts the mouse colon fibrosis in chronic colitis. A, H&E staining, (B) Masson trichrome staining, and (C) collagen IV immunofluorescent staining from the healthy group, acute colitis group, and chronic colitis group, respectively. Compared with the healthy group and the acute colitis group, the GSI score is greater in the chronic colitis group. Correspondingly, the epithelial deterioration, collagen deposition, and tissue thickening are most severe in the chronic colitis group (n = 5).