Table 2.
Predicative values of DOISNORE50 (A) and DOSISNORE50 scoring vs odds of OSA severity (B).
| (A) Positive predicative value and negative predictive value of DOISNORE at different scores identify best thresholds for identifying patients’ probability of obstructive sleep apnea. | ||||||||
|---|---|---|---|---|---|---|---|---|
| DOISNORE50 Score | Sensitivity | Specificity | PPV | NPV | ||||
| Score ≥ 3 | 98% | 8% | 78% | 62% | ||||
| Score ≥ 4 | 93% | 26% | 80% | 50% | ||||
| Score ≥ 5 | 82% | 42% | 82% | 41% | ||||
| Score ≥ 6 | 58% | 81% | 84% | 34% | ||||
| Score ≥ 7 | 41% | 85% | 91% | 30% | ||||
| Score ≥ 8 | 18% | 96% | 96% | 27% | ||||
| (B) Increasing DOISNORE scoring is also associated with increasing odds ratio of OSA. | |||
|---|---|---|---|
| OR (95% CI) | |||
| DOISNORE50 Score Reference = Score 3 | Mild OSA AHI ≥ 5 events/h | Moderate OSA AHI ≥ 15 events/h | Severe OSA AHI ≥ 30 events/h |
| Score 4 | 2.45 (1.58, 3.80) | 3.32 (2.02, 5.45) | 1.39 (0.84, 2.32) |
| Score 5 | 3.34 (2.21, 5.04) | 2.47 (1.50, 4.06) | 1.73 (1.08, 2.77) |
| Score 6 | 5.21 (3.26, 8.33) | 4.09 (2.50, 6.70) | 1.94 (1.20, 3.20) |
| Score 7 | 6.7 (3.80, 11.70) | 4.7 (2.80, 8.00) | 5.2 (3.30, 8.10) |
AHI = apnea-hypopnea index, CI = confidence interval, NPV = negative predicative value, OR = odds ratio, OSA = obstructive sleep apnea, PPV = positive predicative value.