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. 2021 Dec 22;24(8):1389–1399. doi: 10.1093/neuonc/noab295

Table 1.

Baseline Characteristics and Outcomes of Germinoma Patients (n = 418)

Variables Number %
Sex Male 320 76.6
Female 98 23.4
Age at diagnosis (years) Median (min–max) 14.4 (3.8–39.1)
Location Suprasellar 142 34
Pineal 130 31.1
Bifocal 69 16.5
Basal ganglia 53 12.7
Other (thalamus, etc.) 24 5.7
M stage M0 334 79.9
M+ 84 20.1
Operation type No surgery 100 23.9
Biopsy 249 59.6
Tumor removal (+biopsy) 69 16.5
Chemotherapy Yes 260 62.2
No 158 37.8
Second malignancy No 414 99
Yes 4 1
Serum βHCG (mIU/mL) Median (min–max) 1.2 (0.0–712.0)
<10 336 87.6
≥10 50 12.0
<50 366 87.6
≥50 20 4.8
Missing 32 7.7
Serum AFP (ng/mL) Median (min–max) 1.5 (0.0–1090.0)
Missing 28 6.7
F/U time (years) Median (min–max) 8.9 (0.5–25.1)
Recurrence No 368 88
Yes 50 12
Survival Alive 400 95.7
Death 18 4.3

Abbreviations: M, metastasis; HCG, human chorionic gonadotropin; AFP, alpha-fetoprotein; F/u, follow-up.