Table 2.
Radiation Doses and Volumes According to Chemotherapy Responses in Patients who Received Chemotherapy
| Response | |||||||
|---|---|---|---|---|---|---|---|
| CR | VGPR | PR | SD | PD | P value | ||
| RT volume | Focal | 16(16.0) | 7(25.9) | 9(11.8) | 6(33.3) | 1(20) | 0.700 |
| Whole ventricle | 44(44.0) | 10(37.0) | 29(38.2) | 4(22.2) | 2(40) | ||
| Craniospinal | 39(39.0) | 10(37.0) | 37(48.7) | 8(44.4) | 2(40) | ||
| Whole brain | 1(1.0) | 0(0) | 1(1.3) | 0(0) | 0(0) | ||
| Tumor dose | Median (min–max) | 30.6 (19.8–54.0) | 39.6 (25.15–54.0) | 39.6 (3.2–59.15) | 39.6 (23.4–55.8) | 39.6 (90.6–45.0) | 0.002 |
| CSI dose | Median (min–max) | 23.4 (19.8–39.0) | 23.4 (19.8–30.0) | 20.25 (16.2–36.0) | 21.9 (19.5–36.0) | 19.65 (19.5–19.8) | 0.614 |
| WVI dose | Median (min–max) | 19.8 (16.2–39.3) | 24.0 (19.8–30.0) | 19.8 (19.8–45.0) | 21.9(19.8–24.0) | 19.8 (18.0–24.9) | 0.038 |
Abbreviations: RT, radiotherapy; CR, complete response; VGPR, very good partial response; PR, partial response; SD, stable disease; PD, progressive disease; CSI, craniospinal irradiation; WVI, whole ventriclar irradiation.