Table 3.

Univariate and Multivariate Logistic Regression Analysis of LMD for Surgical Patients with MBM

Univariate
Covariate	Level	N	Odds Ratio(95% CI)	OR P-value	Overall P-value
Gender	Female	132	1.74 (0.87–3.48)	.116	.116
	Male	243	-	-
Dural metastasis	Yes	29	2.77 (1.04–7.35)	.041	.041
	No	337	-	-
Intraventricular metastasis	Yes	10	6.94 (1.86–25.88)	.004	.004
	No	365	-	-
Tumor bordering ventricle/ cistern	Yes	88	2.97 (1.46–6.02)	.003	.003
	No	287	-	-
Number of lesions bordering ventricle/ cistern	>2	4	4.45 (0.44–44.76)	.205	.019
	2	7	5.34 (0.97–29.28)	.054
	1	77	2.71 (1.28–5.74)	.009
	0	287	-	-
Ventricular entry during surgery	Yes	39	4.82 (2.15–10.82)	<.001	<.001
	No	332	-	-
Location of brain metastases	Infratentorial/ Both	44	2.40 (1.02–5.67)	.045	.045
	Supratentorial	331	-	-
Chemotherapy before initial MBM diagnosis	Yes	63	0.42 (0.13–1.42)	.165	.165
	No	312	-	-
Chemotherapy after initial MBM diagnosis	Yes	172	1.36 (0.68–2.70)	.383	.383
	No	203	-	-
Immune therapy before Initial MBM diagnosis	Yes	125	1.15 (0.56–2.35)	.710	.710
	No	250	-	-
Immune therapy after initial MBM diagnosis	Yes	175	0.70 (0.35–1.42)	.327	.327
	No	200	-	-
Radiation	SRS/FSRT	206	0.83 (0.37–1.84)	.645	.366
	WBRT ± SRS	86	0.45 (0.15–1.38)	.163
	None	83	-	-
Tumor bordering ventricle w/surgery & ventricular entry	Yes	30	3.12 (1.03–9.48)	.045	.045
	No	58	-	-
Tumor bordering ventricle w/surgery	SRS/FSRT	51	0.29 (0.09–0.98)	.047	.040
	WBRT ± SRS	19	0.09 (0.01–0.81)	.032
	None	18	-	-
Multivariate
Covariate	Level		Odds Ratio(95% CI)	OR P-value	Overall P-value
Dural metastasis	Yes		3.47 (1.22–9.85)	.020	.020
	No		-	-
Intraventricular metastasis	Yes		4.56 (1.01–20.50)	.048	.048
	No		-	-
Ventricular entry during surgery	Yes		4.52 (1.86–11.03)	<.001	<.001
	No		-	-
Location of brain metastases	Infratentorial/ Both		2.89 (1.14–7.35)	.025	.025
	Supratentorial		-	-