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. 2022 Jul 15;65(14):9662–9677. doi: 10.1021/acs.jmedchem.2c00704

Figure 4.

Figure 4

X-ray co-crystal structure of 24 in EGFR LR/TM, highlighting interactions of the sulfone substituent with Lys716 and Lys728 (PDB: 8D76).