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(A) Activity of 30 in NOD SCID mice bearing engineered Ba/F3 (EGFR L858R/T790M/C797S) tumors. (B) Activity of 30 in NOD SCID mice bearing engineered Ba/F3 (EGFR ex19del/T790M/C797S) tumors. (C) Activity of 30 and osimertinib in EGFR ex19del/T790M/C797S PDX model.
