FIG. 8.

Potential NarP binding sites in the aniA upstream region. The plus-strand sequence of the region from −130 to −67 from the sigma 70-type promoter transcription start site is presented. NarL heptamers and their direction are indicated by arrows. Nucleotides which do not match the E. coli consensus are indicated by outlined letters. The E. coli consensus is indicated at the bottom (Y, C or T; M, C or A). As the binding site sequence for gonococcal NarP is unknown, any of these sites is a candidate. (A) A single 7-2-7 motif consisting of an inverted repeat of the heptamer separated by 2 bp was found. Heptamers are also indicated by bold type and underlining. (B) Two similar heptamer inverted repeats in a 7-1-7 arrangement (heptamers separated by 1 bp). Heptamers are also indicated by bold type and underlining. (C) Remaining unpaired half sites.