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. 2022 Jul 15;13(29):6674–6679. doi: 10.1021/acs.jpclett.2c01171

Scheme 1. Molecular Structure of the Aβ16–22 Peptide.

Scheme 1

At neutral pH: LYS and the N-terminal group are protonated and positively charged, while the GLU and C-terminal are deprotonated and negatively charged. Under acidic conditions the carboxyl group of GLU and that of the C-terminus are neutral as they are both protonated.