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BLI of transplanted fibroblasts into wild-type BALB/c mice as an allogeneic recipient and into immune-deficient RAG−/− and NSG mice (A, B). (n = 5–8) and P values are *0.05, **0.005, and ***0.0001. Measurement of light emission (Log photons/second/cm2/sr) in regions of interest (ROIs) was used to quantify the bioluminescent signals. The red dashed line represents the background signal level detected from skin. BLI: bioluminescence imaging; NSG: γ chain–deficient NOD-SCID.
