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. 2022 Aug 1;22:369. doi: 10.1186/s12876-022-02449-w

Table 1.

Comparison of patient characteristics according to vascular invasion

Characteristics Total MVI Grade
Negative Positive P Low High P
Age 175 54.339 (10.584) 53.383 (10.742) 0.573 52.250 (10.606) 54.677 (10.587) 0.1780
Recurrence (months) 175 30.67 ± 23.43 22.18 ± 18.30 0.012 25.97 ± 20.67 21.72 ± 18.92 0.186
Metastasis (months) 175 30.08 ± 23.67 21.76 ± 18.96 0.017 26.03 ± 21.33 20.22 ± 18.79 0.077
HBsAg 0.080 0.590
 Negative 26 21 (80.77) 5 (19.23) 6 (23.08) 20 (76.92)
 Positive 149 94 (63.09) 55 (36.91) 42 (28.19) 107 (71.81)
HBeAg 0.706 0.266
 Negative 117 78 (66.67) 39 (33.33) 29 (24.79) 88 (75.21)
 Positive 58 37 (63.79) 21 (36.21) 19 (32.76) 39 (67.24)
Cirrhosis 0.522 0.011
 Negative 46 32 (69.57) 14 (30.43) 6 (13.04) 40 (86.96)
 Positive 129 83 (64.34) 46 (35.66) 42 (32.56) 87 (67.44)
AFP (ng/L) 0.002 0.030
  > 0 < 20 81 63 (77.78) 18 (22.22) 30(37.04) 51 (62.96)
 > 20 < 400 58 36 (62.07) 22 (37.93) 11 (18.97) 47 (81.03)
 ≥ 400 36 16 (44.44) 20 (55.56) 7 (19.44) 29 (80.56)
MRI feature
Tumor Number 0.005 0.019
 Single 145 102 (70.34) 43 (29.66) 45 (31.03) 100 (68.97)
 Multiple 30 13 (43.33) 17 (56.67) 3 (10.00) 27 (90.00)
Tumor size (cm) 0.030 0.979
 < 5 131 92 (70.23) 39 (29.77) 36 (27.48) 95 (72.52)
 ≥ 5 44 23 (52.27) 21 (47.73) 12 (27.27) 32 (72.73)
Capsule 0.020 0.011
 Negative 117 70 (59.83) 47 (40.17) 25 (21.37) 92 (78.63)
 Positive 58 45 (77.59) 13 (22.41) 23 (39.66) 35 (60.34)
Lipid 0.609 0.078
 Negative 121 81 (66.94) 40 (33.06) 38 (31.40) 83 (68.60)
 Positive 54 34 (62.96) 20 (37.04) 10 (18.52) 44 (81.48)
Arterial rim enhancement 0.001 0.451
 Negative 94 72 (76.60) 22 (23.40) 28 (29.79) 66 (70.21)
 Positive 81 43 (53.09) 38 (46.91) 20 (24.69) 61 (75.31)
Arterial peritumoral enhancement  < 0.001 0.396
 Negative 152 111 (73.03) 41 (26.97) 40 (26.32) 112 (73.68)
 Positive 23 4 (17.39) 19 (82.61) 8 (34.78) 15 (65.22)
Tumor margin  < 0.001 0.883
 Smooth 75 61 (81.33) 14 (18.67) 21 (28.00) 54 (72.00)
 Non-smooth 100 54 (54.00) 46 (46.00) 27 (27.00) 73 (73.00)
Tumor hypointensity on HBP 0.291 0.177
 Yes 161 104 (64.60) 57 (35.40) 42 (26.09) 119 (73.91)
 No 14 11 (78.57) 3 (21.43) 6 (42.86) 8 (57.14)
Peritumoral hypointensity on HBP  < 0.001 0.178
 Absent 146 106 (72.60) 40 (27.40) 43 (29.45) 103 (70.55)
 Present 29 9 (31.03) 20 (68.97) 5 (17.24) 24 (82.76)
Shape 0.854 0.044
 Round 58 40 (68.97) 18 (31.03) 23 (39.66) 35 (60.34)
 Oval 20 14 (70.00) 6 (30.00) 6 (30.00) 14 (70.00)
 Lobulated 65 41 (63.08) 24 (36.92) 11 (16.92) 54 (83.08)
I rregular 32 20 (62.50) 12 (37.50) 8 (25.00) 24 (75.00)