Table 3.
Variables associated with ET initiation by the 12-month interview and ET continuation for at least 12 months after initiation in the pooled sample
ET initiationa | ET continuationb | |
---|---|---|
Independent variables |
aOR (95% CI) (n = 533) |
aOR (95% CI) (n = 410) |
Race | ||
White | Ref. | Ref |
Black/Otherc | 0.66 (0.38-1.13) | 0.85 (0.39-1.85) |
Age, years | 1.01 (0.98-1.03) | 0.97 (0.93-1.00) |
Insurance status | ||
Private | Ref. | Ref |
Public only or otherd | 0.94 (0.52-1.71) | 1.12 (0.47-2.69) |
Chemotherapy | ||
No | Ref. | Ref |
Yes | 3.47 (1.77-6.78)* | 1.23 (0.57-2.66) |
Radiation Therapy | ||
No | Ref. | Ref |
Yes | 3.94 (2.47-6.31)* | 1.42 (0.70-2.89) |
Diabetes | ||
No | Ref. | Ref |
Yes | 0.50 (0.27-0.91)* | 0.84 (0.34-2.04) |
Obesity | ||
No (BMI < 30 kg/m2) | Ref. | Ref |
Yes (BMI ≥ 30 kg/m2) | 1.12 (0.67-1.88) | 1.03 (0.52-2.03) |
Elevated depressed mood | ||
No (CESD < 16) | Ref. | Ref |
Yes (CESD ≥16) | 0.79 (0.41-1.50) | 0.46 (0.19-1.11) |
Menopausal-symptom severity | 1.35 (0.99-1.85) | 0.67 (0.45-0.98)* |
Change in menopausal-symptom severity mean scorese | – | 1.04 (0.66-1.62) |
ET endocrine therapy, BMI body mass index, aOR adjusted odds ratio, CI confidence interval, CESD Center for Epidemiologic Studies Depression scale
a Using diabetes, obesity, elevated depressed mood, and menopausal symptom data from the interview prior to first report of ET initiation. For non-initiators and patients who first reported ever taking ET at baseline, the baseline measures of these four variables were used
b Using diabetes, obesity, elevated depressed mood, and menopausal symptom data from the interview when ET initiation was first reported
c This category includes 216 black, two Asian Indian/Pakistani, two Asian/Pacific Islander, and two unspecified race in the ET initiation model, with one fewer Asian/Pacific Islander in the ET continuation model
d Other insurance status includes no insurance or self-pay
e Change in menopausal-symptom severity mean scores from patient’s first reported use of ET to 12-18 month follow-up of ET continuation among patients who had used ET within 12 months of definitive surgery
* P < 0.05