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. 2022 Aug 1;22:837. doi: 10.1186/s12885-022-09946-x

Table 3.

Variables associated with ET initiation by the 12-month interview and ET continuation for at least 12 months after initiation in the pooled sample

ET initiationa ET continuationb
Independent variables

aOR (95% CI)

(n = 533)

aOR (95% CI)

(n = 410)

Race
 White Ref. Ref
 Black/Otherc 0.66 (0.38-1.13) 0.85 (0.39-1.85)
 Age, years 1.01 (0.98-1.03) 0.97 (0.93-1.00)
Insurance status
 Private Ref. Ref
 Public only or otherd 0.94 (0.52-1.71) 1.12 (0.47-2.69)
Chemotherapy
 No Ref. Ref
 Yes 3.47 (1.77-6.78)* 1.23 (0.57-2.66)
Radiation Therapy
 No Ref. Ref
 Yes 3.94 (2.47-6.31)* 1.42 (0.70-2.89)
Diabetes
 No Ref. Ref
 Yes 0.50 (0.27-0.91)* 0.84 (0.34-2.04)
Obesity
 No (BMI < 30 kg/m2) Ref. Ref
 Yes (BMI ≥ 30 kg/m2) 1.12 (0.67-1.88) 1.03 (0.52-2.03)
Elevated depressed mood
 No (CESD < 16) Ref. Ref
 Yes (CESD ≥16) 0.79 (0.41-1.50) 0.46 (0.19-1.11)
 Menopausal-symptom severity 1.35 (0.99-1.85) 0.67 (0.45-0.98)*
 Change in menopausal-symptom severity mean scorese 1.04 (0.66-1.62)

ET endocrine therapy, BMI body mass index, aOR adjusted odds ratio, CI confidence interval, CESD Center for Epidemiologic Studies Depression scale

a Using diabetes, obesity, elevated depressed mood, and menopausal symptom data from the interview prior to first report of ET initiation. For non-initiators and patients who first reported ever taking ET at baseline, the baseline measures of these four variables were used

b Using diabetes, obesity, elevated depressed mood, and menopausal symptom data from the interview when ET initiation was first reported

c This category includes 216 black, two Asian Indian/Pakistani, two Asian/Pacific Islander, and two unspecified race in the ET initiation model, with one fewer Asian/Pacific Islander in the ET continuation model

d Other insurance status includes no insurance or self-pay

e Change in menopausal-symptom severity mean scores from patient’s first reported use of ET to 12-18 month follow-up of ET continuation among patients who had used ET within 12 months of definitive surgery

* P < 0.05