Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Aug;382(2):167–180. doi: 10.1124/jpet.122.001217

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 by The American Society for Pharmacology and Experimental Therapeutics

PMC Copyright notice

Fig. 5. — Transcriptome analysis of the liver in BALB/c substrains. (A) Sixteen BALB/cJ (four per sex per treatment) and 16 BALB/cByJ mice (four per sex per treatment) data were analyzed blocking the effects of sex and treatment. Sex-combined: a volcano plot shows the distribution of differentially expressed genes in liver homogenate of all mice (J-By expression). Zhx2 is denoted with an arrow. (B) Females: Using only females, data were analyzed blocking the effect of treatment. A volcano plot shows the distribution of differentially expressed PK genes in liver homogenate. For this figure, PK genes include Cyp, Ugt, Abc, and Slc genes. Note the robust downregulation of Ugtb37 in J females, denoted with an arrow. (C) Males: Using only males, data were analyzed blocking the effect of treatment. A volcano plot shows the distribution of differentially expressed PK genes in liver homogenate of male mice.